TAF11 - SIRT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF11	ENSG00000064995	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding vitamin D receptor binding thyroid hormone receptor binding protein heterodimerization activity protein N-terminus binding transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly chromatin binding transcription factor binding transcription factor activity, core RNA polymerase II binding	TAF11 (S. cerevisiae) taf-11.1 (C. elegans) taf-11.3 (C. elegans) taf-11.2 (C. elegans) Taf11 (D. melanogaster)
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)