TSG101 - SIRT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TSG101	ENSG00000074319	No diseases in record	No drugs in record	DNA binding transcription corepressor activity protein binding ligand-dependent nuclear receptor transcription coactivator activity ubiquitin protein ligase binding protein homodimerization activity ubiquitin binding virion binding calcium-dependent protein binding	STP22 (S. cerevisiae) tsg-101 (C. elegans) TSG101 (D. melanogaster)
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)