KDM1A - SIRT1

H. sapiens

SSL interaction

Identifiers

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KDM1A	ENSG00000004487	No diseases in record	No drugs in record	RNA polymerase II transcription factor binding p53 binding chromatin binding transcription factor activity, sequence-specific DNA binding histone deacetylase activity protein binding transcription factor binding oxidoreductase activity enzyme binding ligand-dependent nuclear receptor transcription coactivator activity demethylase activity histone demethylase activity histone demethylase activity (H3-K4 specific) histone demethylase activity (H3-K9 specific) histone demethylase activity (H3-dimethyl-K4 specific) telomeric DNA binding MRF binding transcription regulatory region DNA binding flavin adenine dinucleotide binding androgen receptor binding telomeric repeat-containing RNA binding	Su(var)3-3 (D. melanogaster)
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)