HIVEP1 - SIRT1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
HIVEP1	ENSG00000095951	No diseases in record	No drugs in record	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding DNA binding protein binding sequence-specific DNA binding transcription regulatory region DNA binding metal ion binding	sma-9 (C. elegans) shn (D. melanogaster)
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)