SIRT1 - H2AFY

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
H2AFY	ENSG00000113648	No diseases in record	No drugs in record	rDNA binding RNA polymerase II regulatory region sequence-specific DNA binding RNA polymerase II core promoter sequence-specific DNA binding core promoter sequence-specific DNA binding DNA binding protein binding double-stranded methylated DNA binding enzyme binding protein kinase binding protein serine/threonine kinase inhibitor activity chromatin DNA binding nucleosomal DNA binding transcription regulatory region DNA binding protein heterodimerization activity	HTA1 (S. cerevisiae) HTA2 (S. cerevisiae) His2A:CG31618 (D. melanogaster)