SIRT1 - H2AFY

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SIRT1 ENSG00000096717

No diseases in record

No drugs in record

core promoter sequence-specific DNA binding
p53 binding
transcription corepressor activity
histone deacetylase activity
protein binding
protein C-terminus binding
transcription factor binding
NAD-dependent histone deacetylase activity
deacetylase activity
enzyme binding
protein deacetylase activity
NAD-dependent protein deacetylase activity
nuclear hormone receptor binding
histone binding
identical protein binding
HLH domain binding
bHLH transcription factor binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
mitogen-activated protein kinase binding
NAD+ binding
keratin filament binding
NAD+ ADP-ribosyltransferase activity
HST1 (S. cerevisiae)
SIR2 (S. cerevisiae)
sir-2.1 (C. elegans)
H2AFY ENSG00000113648

No diseases in record

No drugs in record

rDNA binding
RNA polymerase II regulatory region sequence-specific DNA binding
RNA polymerase II core promoter sequence-specific DNA binding
core promoter sequence-specific DNA binding
DNA binding
protein binding
double-stranded methylated DNA binding
enzyme binding
protein kinase binding
protein serine/threonine kinase inhibitor activity
chromatin DNA binding
nucleosomal DNA binding
transcription regulatory region DNA binding
protein heterodimerization activity
HTA1 (S. cerevisiae)
HTA2 (S. cerevisiae)
His2A:CG31618 (D. melanogaster)