SIRT1 - SHMT2

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
SIRT1 ENSG00000096717

No diseases in record

No drugs in record

core promoter sequence-specific DNA binding
p53 binding
transcription corepressor activity
histone deacetylase activity
protein binding
protein C-terminus binding
transcription factor binding
NAD-dependent histone deacetylase activity
deacetylase activity
enzyme binding
protein deacetylase activity
NAD-dependent protein deacetylase activity
nuclear hormone receptor binding
histone binding
identical protein binding
HLH domain binding
bHLH transcription factor binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
mitogen-activated protein kinase binding
NAD+ binding
keratin filament binding
NAD+ ADP-ribosyltransferase activity
HST1 (S. cerevisiae)
SIR2 (S. cerevisiae)
sir-2.1 (C. elegans)
SHMT2 ENSG00000182199

No diseases in record

No drugs in record

chromatin binding
glycine hydroxymethyltransferase activity
protein binding
L-allo-threonine aldolase activity
amino acid binding
pyridoxal phosphate binding
identical protein binding
SHM1 (S. cerevisiae)
SHM2 (S. cerevisiae)