H. sapiens

SSL interaction


Gene Name Gene ID Diseases Drugs GO terms Orthologs
MAP2K4 ENSG00000065559 pancreatic

No drugs in record

protein kinase activity
signal transducer, downstream of receptor, with serine/threonine kinase activity
protein tyrosine kinase activity
protein binding
ATP binding
JUN kinase kinase activity
mitogen-activated protein kinase kinase kinase binding
PBS2 (S. cerevisiae)
sek-3 (C. elegans)
mkk-4 (C. elegans)
sek-6 (C. elegans)
Mkk4 (D. melanogaster)
SIRT1 ENSG00000096717

No diseases in record

No drugs in record

core promoter sequence-specific DNA binding
p53 binding
transcription corepressor activity
histone deacetylase activity
protein binding
protein C-terminus binding
transcription factor binding
NAD-dependent histone deacetylase activity
deacetylase activity
enzyme binding
protein deacetylase activity
NAD-dependent protein deacetylase activity
nuclear hormone receptor binding
histone binding
identical protein binding
HLH domain binding
bHLH transcription factor binding
metal ion binding
NAD-dependent histone deacetylase activity (H3-K9 specific)
mitogen-activated protein kinase binding
NAD+ binding
keratin filament binding
NAD+ ADP-ribosyltransferase activity
HST1 (S. cerevisiae)
SIR2 (S. cerevisiae)
sir-2.1 (C. elegans)