SIRT1 - ELP3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIRT1	ENSG00000096717	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding p53 binding transcription corepressor activity histone deacetylase activity protein binding protein C-terminus binding transcription factor binding NAD-dependent histone deacetylase activity deacetylase activity enzyme binding protein deacetylase activity NAD-dependent protein deacetylase activity nuclear hormone receptor binding histone binding identical protein binding HLH domain binding bHLH transcription factor binding metal ion binding NAD-dependent histone deacetylase activity (H3-K9 specific) mitogen-activated protein kinase binding NAD+ binding keratin filament binding NAD+ ADP-ribosyltransferase activity	HST1 (S. cerevisiae) SIR2 (S. cerevisiae) sir-2.1 (C. elegans)
ELP3	ENSG00000134014	No diseases in record	No drugs in record	protein binding phosphorylase kinase regulator activity H3 histone acetyltransferase activity H4 histone acetyltransferase activity metal ion binding iron-sulfur cluster binding RNA polymerase II core binding histone acetyltransferase activity transferase activity N-acetyltransferase activity catalytic activity transferase activity, transferring acyl groups acetyltransferase activity	ELP3 (S. cerevisiae) Elp3 (D. melanogaster)