TOP2A - UBE2L3

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP2A	ENSG00000131747	No diseases in record	DAUNORUBICIN DOXORUBICIN EPIRUBICIN ETOPOSIDE ETOPOSIDE PHOSPHATE IDARUBICIN MITOXANTRONE PODOFILOX TENIPOSIDE VALRUBICIN	magnesium ion binding DNA binding chromatin binding DNA topoisomerase type II (ATP-hydrolyzing) activity protein kinase C binding protein binding ATP binding protein C-terminus binding DNA-dependent ATPase activity drug binding DNA binding, bending enzyme binding protein homodimerization activity histone deacetylase binding ubiquitin binding protein heterodimerization activity	TOP2 (S. cerevisiae) cin-4 (C. elegans) top-2 (C. elegans)
UBE2L3	ENSG00000185651	No diseases in record	No drugs in record	transcription coactivator activity ubiquitin-protein transferase activity protein binding ATP binding enzyme binding ubiquitin protein ligase binding ubiquitin conjugating enzyme activity ubiquitin-protein transferase activator activity	UBC4 (S. cerevisiae) UBC5 (S. cerevisiae) Ubc10 (D. melanogaster)