TPR - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TPR	ENSG00000047410	papillary thyroid NSCLC	No drugs in record	molecular_function chromatin binding mRNA binding nucleocytoplasmic transporter activity protein binding tubulin binding heat shock protein binding protein homodimerization activity mitogen-activated protein kinase binding dynein complex binding transporter activity protein anchor	Mtor (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)