TGFBR2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TGFBR2	ENSG00000163513	head and neck colorectal	No drugs in record	transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity transforming growth factor beta-activated receptor activity transforming growth factor beta receptor activity, type II protein binding ATP binding glycosaminoglycan binding mitogen-activated protein kinase kinase kinase binding type I transforming growth factor beta receptor binding SMAD binding metal ion binding transforming growth factor beta binding	No GO terms in record
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)