FUS - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
FUS	ENSG00000089280	liposarcoma AML Ewing sarcoma angiomatoid fibrous histiocytoma fibromyxoid sarcoma	No drugs in record	nucleotide binding DNA binding transcription coactivator activity RNA binding protein binding zinc ion binding estrogen receptor binding myosin V binding ionotropic glutamate receptor binding identical protein binding retinoid X receptor binding thyroid hormone receptor binding mRNA binding	No GO terms in record
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)