EXT2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EXT2	ENSG00000151348	exostoses osteosarcoma	No drugs in record	protein binding glucuronosyltransferase activity transferase activity, transferring glycosyl groups heparan sulfate N-acetylglucosaminyltransferase activity metal ion binding protein heterodimerization activity glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity protein homodimerization activity acetylglucosaminyltransferase activity	No GO terms in record
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)