CSF3R - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CSF3R	ENSG00000119535	aCML CNL leukaemia lymphoma and MDS associated with severe congenital neutropenia CMML de novo AML MDS	FILGRASTIM PEGFILGRASTIM	receptor activity cytokine receptor activity protein binding granulocyte colony-stimulating factor binding	No GO terms in record
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)