IRS2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
IRS2	ENSG00000185950	No diseases in record	No drugs in record	signal transducer activity Ras guanyl-nucleotide exchange factor activity insulin receptor binding protein binding 1-phosphatidylinositol-3-kinase activity protein kinase binding protein phosphatase binding protein domain specific binding phosphatidylinositol 3-kinase binding phosphatidylinositol-4,5-bisphosphate 3-kinase activity 14-3-3 protein binding	chico (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)