TAF4 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF4	ENSG00000130699	No diseases in record	No drugs in record	DNA binding transcription coactivator activity protein binding transcription factor binding protein heterodimerization activity transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription factor activity, sequence-specific DNA binding chromatin binding RNA polymerase II activating transcription factor binding TFIIA-class transcription factor binding transcription factor activity, core RNA polymerase II binding	taf-4 (C. elegans) Taf4 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)