SIAH2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SIAH2	ENSG00000181788	No diseases in record	No drugs in record	transcription corepressor activity ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity ubiquitin conjugating enzyme binding ubiquitin protein ligase activity	siah-1 (C. elegans) sina (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)