Gene Name | Gene ID | Diseases | Drugs | GO terms | Orthologs |
---|---|---|---|---|---|
DEK | ENSG00000124795 |
AML |
No drugs in record |
DNA binding chromatin binding histone binding |
Dek (D. melanogaster) |
TOP1 | ENSG00000198900 |
AML* |
IRINOTECAN |
core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity |
TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster) |