SOCS2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SOCS2	ENSG00000120833	No diseases in record	No drugs in record	protein kinase inhibitor activity SH3/SH2 adaptor activity growth hormone receptor binding insulin-like growth factor receptor binding protein binding JAK pathway signal transduction adaptor activity	Socs44A (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)