E2F2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
E2F2	ENSG00000007968	No diseases in record	No drugs in record	core promoter binding DNA binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding protein dimerization activity protein heterodimerization activity transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding RNA polymerase II regulatory region DNA binding	E2f1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)