CASP10 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CASP10	ENSG00000003400	No diseases in record	No drugs in record	cysteine-type endopeptidase activity protein binding ubiquitin protein ligase binding death effector domain binding cysteine-type endopeptidase activity involved in apoptotic signaling pathway	Dredd (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)