TOP1 - SREBF2

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)
SREBF2	ENSG00000198911	No diseases in record	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding protein binding protein C-terminus binding protein dimerization activity E-box binding C-8 sterol isomerase activity	sbp-1 (C. elegans)