U2AF2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
U2AF2	ENSG00000063244	No diseases in record	No drugs in record	nucleotide binding protein binding poly-pyrimidine tract binding enzyme binding pre-mRNA 3'-splice site binding C2H2 zinc finger domain binding	uaf-1 (C. elegans) U2af50 (D. melanogaster) LS2 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)