NOTCH2 - TOP1

H. sapiens

SSL interaction

Identifiers

Gene Name Gene ID Diseases Drugs GO terms Orthologs
NOTCH2 ENSG00000134250 marginal zone lymphoma
DLBCL
bladder

No drugs in record

receptor activity
calcium ion binding
protein binding
transcription factor activity, ligand-activated RNA polymerase II transcription factor binding
N (D. melanogaster)
TOP1 ENSG00000198900 AML*
IRINOTECAN
core promoter sequence-specific DNA binding
DNA binding
chromatin binding
DNA topoisomerase type I activity
protein binding
isomerase activity
DNA topoisomerase activity
TOP1 (S. cerevisiae)
top-1 (C. elegans)
Top1 (D. melanogaster)