EIF4A1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EIF4A1	ENSG00000161960	No diseases in record	No drugs in record	RNA cap binding double-stranded RNA binding mRNA binding translation initiation factor activity ATP-dependent RNA helicase activity helicase activity protein binding ATP binding translation factor activity, RNA binding	FAL1 (S. cerevisiae) inf-1 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)