STAG1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
STAG1	ENSG00000118007	colorectal cancer AML	No drugs in record	transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding chromatin binding protein binding	IRR1 (S. cerevisiae) scc-3 (C. elegans) SA (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)