REL - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
REL	ENSG00000162924	Hodgkin lymphoma	No drugs in record	RNA polymerase II distal enhancer sequence-specific DNA binding transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding DNA binding RNA polymerase II regulatory region sequence-specific DNA binding	Dl (D. melanogaster) Dif (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)