TAF8 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TAF8	ENSG00000137413	No diseases in record	No drugs in record	protein binding protein heterodimerization activity transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly transcription factor activity, core RNA polymerase II binding	taf-8 (C. elegans) SA (D. melanogaster) Taf8 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)