EED - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
EED	ENSG00000074266	malignant peripheral nerve sheath tumours MDS and related lung adenocarcinoma	No drugs in record	chromatin binding protein binding histone methyltransferase activity identical protein binding	mes-6 (C. elegans) esc (D. melanogaster) escl (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)