SUFU - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
SUFU	ENSG00000107882	medulloblastoma	No drugs in record	transcription corepressor activity signal transducer activity protein binding beta-catenin binding transcription factor binding protein kinase binding	Su(fu) (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)