KEAP1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
KEAP1	ENSG00000079999	NSCLC breast carcinoma	DIMETHYL FUMARATE	protein binding transcription factor binding ubiquitin-protein transferase activity actin binding protein homodimerization activity	Keap1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)