PER1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PER1	ENSG00000179094	AML CMML	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity, transcription factor binding transcription factor binding kinase binding chromatin DNA binding ubiquitin protein ligase binding E-box binding molecular_function L-proline transmembrane transporter activity	lin-42 (C. elegans) per (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)