RBX1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RBX1	ENSG00000100387	No diseases in record	No drugs in record	ubiquitin-protein transferase activity protein binding zinc ion binding ligase activity NEDD8 transferase activity ubiquitin protein ligase binding protein complex binding ubiquitin-ubiquitin ligase activity ubiquitin protein ligase activity cullin family protein binding	HRT1 (S. cerevisiae) rbx-1 (C. elegans) Roc1a (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)