| Gene Name | Gene ID | Diseases | Drugs | GO terms | Orthologs |
|---|---|---|---|---|---|
| LIG4 | ENSG00000174405 |
No diseases in record |
No drugs in record |
DNA binding DNA ligase activity DNA ligase (ATP) activity protein binding ATP binding protein C-terminus binding ligase activity metal ion binding |
DNL4 (S. cerevisiae) lig-4 (C. elegans) Lig4 (D. melanogaster) |
| TOP1 | ENSG00000198900 |
AML* |
IRINOTECAN |
core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity |
TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster) |
