ABI2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABI2	ENSG00000138443	No diseases in record	No drugs in record	DNA binding protein binding cytoskeletal adaptor activity SH3 domain binding kinase binding ubiquitin protein ligase binding protein complex binding proline-rich region binding Rac GTPase binding	abi-1 (C. elegans) Abi (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)