ABI1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ABI1	ENSG00000136754	AML	No drugs in record	protein binding cytoskeletal protein binding SH3 domain binding protein tyrosine kinase activator activity protein complex binding cadherin binding involved in cell-cell adhesion	abi-1 (C. elegans) Abi (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)