CBFB - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBFB	ENSG00000067955	AML	No drugs in record	DNA binding transcription factor activity, sequence-specific DNA binding transcription cofactor activity transcription coactivator activity protein binding	Bro (D. melanogaster) Bgb (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)