ACVR2A - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ACVR2A	ENSG00000121989	large intestine carcinoma stomach carcinoma pancreatic carcinoma biliary tract oesophagus	No drugs in record	protein serine/threonine kinase activity transmembrane receptor protein serine/threonine kinase activity signal transducer, downstream of receptor, with serine/threonine kinase activity protein binding ATP binding coreceptor activity growth factor binding PDZ domain binding inhibin binding protein self-association metal ion binding BMP receptor activity activin-activated receptor activity activin binding	put (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)