RXRA - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RXRA	ENSG00000186350	No diseases in record	ACITRETIN ADAPALENE ALITRETINOIN BEXAROTENE ETRETINATE	RNA polymerase II regulatory region sequence-specific DNA binding DNA binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity retinoic acid receptor activity transcription coactivator activity RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding 9-cis retinoic acid receptor activity protein binding zinc ion binding enzyme binding chromatin DNA binding vitamin D receptor binding sequence-specific DNA binding retinoic acid-responsive element binding protein heterodimerization activity transcription regulatory region DNA binding vitamin D response element binding	usp (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)