THRB - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
THRB	ENSG00000151090	No diseases in record	DEXTROTHYROXINE LEVOTHYROXINE LIOTHYRONINE	DNA binding transcription factor activity, sequence-specific DNA binding steroid hormone receptor activity transcription corepressor activity thyroid hormone receptor activity protein binding zinc ion binding enzyme binding chromatin DNA binding sequence-specific DNA binding thyroid hormone binding	EcR (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)