GNAS - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
GNAS	ENSG00000087460	pituitary adenoma pancreatic intraductal papillary mucinous neoplasm fibrous dysplasia	No drugs in record	GTPase activity signal transducer activity insulin-like growth factor receptor binding protein binding GTP binding G-protein beta/gamma-subunit complex binding beta-2 adrenergic receptor binding D1 dopamine receptor binding mu-type opioid receptor binding ionotropic glutamate receptor binding metal ion binding corticotropin-releasing hormone receptor 1 binding	GPA1 (S. cerevisiae) Galphas (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)