TCF12 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
TCF12	ENSG00000140262	extraskeletal myxoid chondrosarcoma	No drugs in record	RNA polymerase II core promoter proximal region sequence-specific DNA binding transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding transcription factor activity, sequence-specific DNA binding protein binding transcription factor binding enhancer binding cAMP response element binding protein homodimerization activity bHLH transcription factor binding SMAD binding protein heterodimerization activity E-box binding HMG box domain binding transcription regulatory region DNA binding	hlh-2 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)