CHMP4B - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CHMP4B	ENSG00000101421	No diseases in record	No drugs in record	protein binding identical protein binding protein homodimerization activity cadherin binding involved in cell-cell adhesion	SNF7 (S. cerevisiae) vps-32.1 (C. elegans) vps-32.2 (C. elegans) shrb (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)