PAX3 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
PAX3	ENSG00000135903	alveolar rhabdomyosarcoma	No drugs in record	transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding HMG box domain binding	pax-3 (C. elegans) gsb (D. melanogaster) prd (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)