DVL2 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
DVL2	ENSG00000004975	No diseases in record	No drugs in record	frizzled binding protein binding protein kinase binding protein domain specific binding protein binding, bridging identical protein binding protein self-association Rac GTPase binding	dsh-2 (C. elegans) dsh-1 (C. elegans) mig-5 (C. elegans) dsh (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)