CBLC - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
CBLC	ENSG00000142273	AML	No drugs in record	phosphotyrosine residue binding signal transducer activity epidermal growth factor receptor binding calcium ion binding zinc ion binding ligase activity SH3 domain binding receptor tyrosine kinase binding ubiquitin protein ligase activity	sli-1 (C. elegans) Cbl (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)