ITPR1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
ITPR1	ENSG00000150995	No diseases in record	No drugs in record	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity calcium ion binding protein binding calcium ion transmembrane transporter activity calcium-release channel activity calcium channel inhibitor activity phosphatidylinositol binding inositol 1,4,5 trisphosphate binding	itr-1 (C. elegans)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)