RAD1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RAD1	ENSG00000113456	No diseases in record	No drugs in record	damaged DNA binding protein binding 3'-5' exonuclease activity exodeoxyribonuclease III activity DNA binding nuclease activity single-stranded DNA binding endodeoxyribonuclease activity hydrolase activity endonuclease activity single-stranded DNA endodeoxyribonuclease activity	mrt-2 (C. elegans) Rad1 (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)