RRN3 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
RRN3	ENSG00000085721	No diseases in record	No drugs in record	RNA polymerase I CORE element sequence-specific DNA binding RNA polymerase binding transcription factor activity, core RNA polymerase I binding rDNA binding RNA polymerase I transcription factor binding RNA polymerase I core binding transcription factor activity, RNA polymerase I transcription factor binding transcription factor activity, RNA polymerase I CORE element sequence-specific binding	RRN3 (S. cerevisiae) C36E8.1 (C. elegans) Tif-IA (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)