MTA1 - TOP1

SSL interaction

Gene Name	Gene ID	Diseases	Drugs	GO terms	Orthologs
MTA1	ENSG00000182979	No diseases in record	No drugs in record	core promoter sequence-specific DNA binding core promoter binding RNA polymerase II repressing transcription factor binding chromatin binding transcription factor activity, sequence-specific DNA binding transcription coactivator activity transcription corepressor activity histone deacetylase activity protein binding zinc ion binding	lin-40 (C. elegans) MTA1-like (D. melanogaster)
TOP1	ENSG00000198900	AML*	IRINOTECAN	core promoter sequence-specific DNA binding DNA binding chromatin binding DNA topoisomerase type I activity protein binding isomerase activity DNA topoisomerase activity	TOP1 (S. cerevisiae) top-1 (C. elegans) Top1 (D. melanogaster)